Explore our single nucleus RNA sequencing data of Stickleback Brain with SHINYAPP
RESEARCH ShinyApp is an interactive web application that allows users to explore gene activity in the brain of the three-spined stickleback at single-nucleus resolution. Through an intuitive interface, users can browse different cell types, visualize gene expression patterns, and gain insights into how brain cells are organized and function. The platform enables users to visualize […]
Behavioural variability and repeatability in adult zebrafish (Danio rerio) using the novel tank dive test
RESEARCH Despite the reach of in situ hybridization (ISH) in developmental biology, it has rarely been used at scale. The major limitation has been the throughput of the assay, which typically relies upon labor intensive manual steps. The goal of this study was to develop a fully automated hybridization chain reaction (HCR) pipeline capable of large-scale gene […]
4-Automated, high-throughput in-situ hybridization of Lytechinus pictus embryos
RESEARCH Despite the reach of in situ hybridization (ISH) in developmental biology, it has rarely been used at scale. The major limitation has been the throughput of the assay, which typically relies upon labor intensive manual steps. The goal of this study was to develop a fully automated hybridization chain reaction (HCR) pipeline capable of large-scale gene […]
2-CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase
RESEARCH Despite the reach of in situ hybridization (ISH) in developmental biology, it has rarely been used at scale. The major limitation has been the throughput of the assay, which typically relies upon labor intensive manual steps. The goal of this study was to develop a fully automated hybridization chain reaction (HCR) pipeline capable of large-scale gene […]
Rennison lab conducts exciting field work in British Columbia
NEWS In Summer 2025, members of the Rennison Lab at UC San Diego traveled to the breathtaking landscapes of British Columbia, Canada, for a hands-on research expedition. Their goal was to collect threespine stickleback fish for a collaborative effort focused on establishing new laboratory lines and performing whole-genome resequencing. This fieldwork marks an important step […]